In the context of the anime, this statement refers to the Orochi, which is the enemy of human beings.
However, based on the text alone, what species of animal comes to mind?
“greed, avarice, pride“: common traits of human beings
“devouring every living thing“: humans consume animals, plants and fungi
“burning the land“: humans slash-and-burn to clear forests
“drying the seas“: humans build dams in rivers
“destruction“: pollution by humans has ruined the natural landscape
Therefore, who is the true enemy of human beings?